Chicago White Sox vs St. Louis Cardinals Preview: Odds, Spread, Time & TV (September 12, 2026)

The Chicago White Sox (75-71) visit the St. Louis Cardinals (72-75) on Saturday, September 12, 2026 at Busch Stadium. First pitch is set for 7:15 PM ET. TV: MLB Network, MLB.TV, CHSN, Cardinals.TV.

Chicago White Sox vs St. Louis Cardinals Odds & Preview Info

Matchup Chicago White Sox @ St. Louis Cardinals
Records Chicago White Sox 75-71 | St. Louis Cardinals 72-75
Run Line CHW +1.5 | STL -1.5
Moneyline Chicago White Sox: -102 | St. Louis Cardinals: -118
Total 8.5
Venue Busch Stadium
Date / Time Saturday, September 12, 2026 — 7:15 PM ET
TV / How to Watch MLB Network, MLB.TV, CHSN, Cardinals.TV
Probable Pitchers Chicago White Sox: Luis Castillo | St. Louis Cardinals: Kyle Leahy

Odds shown via public sportsbooks (lines move — verify before betting).

Chicago White Sox Preview & Probable Pitcher

The Chicago White Sox enter Saturday at 75-71 and travel to face the St. Louis Cardinals at Busch Stadium. Slated starter: Luis Castillo.

Track the run line, moneyline, and total listed above for this odds preview. Double-check probable pitchers and any late roster moves closer to first pitch at 7:15 PM ET.

St. Louis Cardinals Preview & Probable Pitcher

The St. Louis Cardinals sit at 72-75 hosting from Busch Stadium. Probable starter: Kyle Leahy.

How to watch: MLB Network, MLB.TV, CHSN, Cardinals.TV. Odds and totals can shift through the afternoon — recheck your book for the latest Chicago White Sox vs St. Louis Cardinals line before the September 12, 2026 first pitch.

Where to Watch Chicago White Sox vs St. Louis Cardinals

Tune in Saturday, September 12, 2026 at 7:15 PM ET from Busch Stadium. Broadcast coverage: MLB Network, MLB.TV, CHSN, Cardinals.TV.