The No. 9 Ole Miss Rebels (3-1) visit the Vanderbilt Commodores (3-2) on Saturday, October 10, 2026 at FirstBank Stadium, Nashville, TN. Kickoff is scheduled for 3:30 PM ET, and the game airs on ESPN. DraftKings lists the spread at MISS -10 with a total of 59.5; moneylines are Ole Miss -380 · Vanderbilt +300. Below is our Ole Miss vs Vanderbilt preview with the latest odds, point spread, moneyline, over/under, kickoff time, TV channel and where to watch, plus a look at each team’s season so far, head coach and key players. Lines may move before kickoff.
Ole Miss vs Vanderbilt Odds, Spread, Kickoff Time & TV
| Matchup detail | Line / info |
|---|---|
| Matchup | No. 9 Ole Miss at Vanderbilt |
| Records | Ole Miss 3-1 · Vanderbilt 3-2 |
| Spread | MISS -10 |
| Moneyline | Ole Miss -380 · Vanderbilt +300 |
| Total | 59.5 |
| Venue | FirstBank Stadium, Nashville, TN |
| Date/Time | Saturday, October 10, 2026 · 3:30 PM ET |
| TV / How to Watch | ESPN |
| Head Coaches | Ole Miss: HC Pete Golding, OC John David Baker · Vanderbilt: HC Clark Lea, OC Tim Beck |
Ole Miss Preview: Season So Far, Coach & Key Players
Season so far: The Ole Miss Rebels are 3-1 overall, 1-1 in SEC play, and they are ranked No. 9 in this week’s AP Top 25. Results to date: Sep 6 — W 41-38 vs Louisville (neutral site); Sep 12 — W 41-9 vs Charlotte; Sep 19 — W 32-24 vs LSU; Sep 26 — L 52-28 at Florida. Most recently, Ole Miss lost to Florida 52-28 on the road. Through 4 games, Ole Miss is averaging 35.5 points scored and 30.8 points allowed per game.
Head coach: Pete Golding (head coach since 2025). Offensive coordinator: John David Baker. Defensive coordinator: Bryan Brown.
Key players (2026 season stats):
- Passing leader: Trinidad Chambliss (QB) — 102/144, 1,222 yards, 8 TD, 3 INT
- Rushing leader: Kewan Lacy (RB) — 39 carries, 191 yards, 4 TD
- Receiving leader: Deuce Alexander (WR) — 27 receptions, 429 yards, 4 TD
- Sacks leader: Blake Purchase (DE) — 1.5 sacks
- Tackles leader: Keaton Thomas (LB) — 29 total tackles
Strengths: An offense scoring 35.5 points per game; Trinidad Chambliss’s passing volume (1,222 yards). Questions: A defense giving up 30.8 points per game; the response to a 52-28 loss at Florida.
Vanderbilt Preview: Season So Far, Coach & Key Players
Season so far: The Vanderbilt Commodores are 3-2 overall, 0-2 in SEC play. Results to date: Sep 5 — W 28-9 vs Austin Peay; Sep 12 — W 35-26 vs Delaware; Sep 19 — W 35-31 vs NC State; Sep 26 — L 21-15 at Auburn; Oct 3 — L 38-14 at Georgia. Most recently, Vanderbilt lost to Georgia 38-14 on the road. Through 5 games, Vanderbilt is averaging 25.4 points scored and 25.0 points allowed per game.
Head coach: Clark Lea (head coach since 2021). Offensive coordinator: Tim Beck. Defensive coordinator: Steve Gregory.
Key players (2026 season stats):
- Passing leader: Jared Curtis (QB) — 63/98, 746 yards, 4 TD, 3 INT
- Rushing leader: Sedrick Alexander (RB) — 45 carries, 200 yards, 4 TD
- Receiving leader: Junior Sherrill (WR) — 28 receptions, 474 yards, 3 TD
- Sacks leader: Nick Rinaldi (LB) — 3.5 sacks
- Tackles leader: CJ Heard (S) — 38 total tackles
Strengths: The production of Jared Curtis (63/98, 746 yards, 4 TD, 3 INT). Questions: A defense allowing 25.0 points per game; the response to a 38-14 loss at Georgia.
How to Watch Ole Miss vs Vanderbilt
- Date: Saturday, October 10, 2026
- Kickoff: 3:30 PM ET
- Venue: FirstBank Stadium, Nashville, TN
- TV / Streaming: ESPN
Odds: DraftKings lines reported via ESPN on October 5, 2026. Lines may move before kickoff. Records, results and season stats via ESPN; coaching staffs per 2026 staff listings. This page is an informational matchup preview only.