Our Eagles vs Jaguars preview covers the latest odds, point spread, moneyline, total, kickoff time, TV channel and where to watch for the NFL Week 5 matchup between the Philadelphia Eagles (2-2) and the Jacksonville Jaguars (3-1) on Sunday, October 11, 2026, at Tottenham Hotspur Stadium in London, England, a neutral-site international game with Jacksonville as the designated home team. Kickoff is 9:30 AM ET (2:30 PM BST local time, 6:30 AM PT), and the game airs on NFL Network.
Week 5 storyline: The Jaguars are the designated home team for this London game at Tottenham Hotspur Stadium, the first of two straight London games for Jacksonville. Philadelphia has lost two straight after a 2-0 start, including a 24-20 home loss to the Rams in which it gave up a 10-point fourth-quarter lead, and its injury list now includes RB Saquon Barkley and WR DeVonta Smith (both hamstring). Jacksonville is 3-1 after Trevor Lawrence’s first career win over Cincinnati (AP, ESPN).
As of Tuesday, Oct. 6, 2026, 2:18 AM PT (5:18 AM ET), DraftKings via ESPN lists the Jaguars as 7-point favorites over the Eagles, with the moneyline at Eagles +235 / Jaguars -290 and the over/under at 42.5. Since the open, the spread has moved from PHI -2.5 to JAX -7 and the total has moved from 44.5 to 42.5. Below are the full Eagles vs Jaguars odds, both team previews, the latest Week 5 injury news and TV details.
Eagles vs Jaguars Odds & Preview Info
| Matchup detail | Line / info |
|---|---|
| Matchup | Philadelphia Eagles vs Jacksonville Jaguars (London; Jacksonville designated home) |
| Records | Eagles 2-2 (1-1 road) · Jaguars 3-1 (2-0 home) |
| Spread | Eagles +7 (-115) · Jaguars -7 (-105) |
| Moneyline | Eagles +235 · Jaguars -290 |
| Total | 42.5 (Over -118 / Under -102) |
| Venue | Tottenham Hotspur Stadium, London, England (neutral site; Jaguars designated home team) |
| Date/Time | Sunday, October 11, 2026 · 9:30 AM ET (2:30 PM BST local time, 6:30 AM PT) |
| TV | NFL Network |
| Head Coaches | Eagles: Nick Sirianni · Jaguars: Liam Coen |
| Starting QBs | Eagles: Jalen Hurts · Jaguars: Trevor Lawrence |
Odds: DraftKings via ESPN as of Tuesday, Oct. 6, 2026, 2:18 AM PT (5:18 AM ET). Opening line: PHI -2.5, total 44.5, moneyline Eagles -130 / Jaguars +110. Line movement: the spread has moved from PHI -2.5 to JAX -7, the total has moved from 44.5 to 42.5, and the moneyline has gone from Eagles -130 / Jaguars +110 at the open to Eagles +235 / Jaguars -290. Spread and total prices are shown in parentheses. Lines can move before kickoff.
Philadelphia Eagles Preview
2026 results through Week 4: Week 1: vs Commanders, W 24-22 · Week 2: at Titans, W 24-20 · Week 3: at Bears, L 7-27 · Week 4: vs Rams, L 20-24. Points: 75 scored, 93 allowed.
Season so far: Philadelphia beat Washington 24-22 by stopping a tying two-point try and won 24-20 at Tennessee on Jalen Hurts’ touchdown pass to Darius Cooper with nine seconds left. Since then, they have lost 27-7 at Chicago and 24-20 at home to the Rams (AP).
Quarterback and key players: Hurts is 68 of 114 for 713 yards with seven touchdowns and three interceptions (ESPN); he was 12 of 27 for 93 yards with two touchdowns against the Rams. Barkley has 182 rushing yards, Smith leads the team with 19 catches for 235 yards, Nolan Smith Jr. has two sacks and LB Jihaad Campbell has 37 tackles.
This week: NFL Network reported that RB Tank Bigsby needs core muscle surgery and is headed to injured reserve, while Barkley is considered week-to-week. C Cam Jurgens entered the concussion protocol Monday, LB Jonathan Greenard (ankle) is day-to-day and CB Quinyon Mitchell was scheduled for knee testing. (ESPN, NFL Network).
Jacksonville Jaguars Preview
2026 results through Week 4: Week 1: vs Browns, W 34-10 · Week 2: at Broncos, L 13-20 · Week 3: vs Patriots, W 35-6 · Week 4: at Bengals, W 22-17. Points: 104 scored, 53 allowed.
Season so far: Jacksonville opened with a 34-10 rout of Cleveland, lost 20-13 at Denver, beat New England 35-6 and won 22-17 at Cincinnati last week, holding on late for Lawrence’s first win over the Bengals (AP).
Quarterback and key players: Lawrence has completed 72 of 104 passes for 843 yards with eight touchdowns and two interceptions (ESPN), including 18 of 23 in Cincinnati. Bhayshul Tuten leads the team with 277 rushing yards, Parker Washington has 16 catches for 228 yards, Josh Hines-Allen has 1.5 sacks and LB Ventrell Miller has 30 tackles.
This week: Liam Coen’s secondary is thin: CBs Christian Braswell (knee) and Montaric Brown (hamstring) are listed out, and safeties Eric Murray (concussion) and Caleb Ransaw (knee) both left the Bengals game (ESPN, Florida Times-Union).
Eagles vs Jaguars Key Injuries
Source: ESPN’s injury tracker as of Tuesday, Oct. 6, 2026, 2:18 AM PT (5:18 AM ET), with team-site, ESPN and NFL Network reporting for context. These are tracker statuses after Week 4, not official game designations: official Week 5 reports for this game run Wednesday through Friday, with game designations on Friday, Oct. 9. Some players listed questionable left Week 4 games and have not been updated yet.
Philadelphia Eagles — Out: RB Tank Bigsby (abdomen surgery); WR DeVonta Smith (hamstring); OT Fred Johnson (knee); OT Lane Johnson (personal); S Marcus Epps (groin); TE Dallas Goedert (knee – MCL sprain); LB Zack Baun (concussion); WR Hollywood Brown (ankle) · Doubtful: none · Questionable: C Cam Jurgens (concussion); RB Saquon Barkley (hamstring); LB Jonathan Greenard (ankle); CB Quinyon Mitchell (knee bruise) · Recent injured reserve moves (ESPN): none since Sept. 22.
Jacksonville Jaguars — Out: CB Christian Braswell (knee); CB Montaric Brown (hamstring) · Doubtful: none · Questionable: S Eric Murray (concussion); S Caleb Ransaw (knee) · Recent injured reserve moves (ESPN): none since Sept. 22.
Context: Philadelphia’s list is long: ESPN’s tracker shows eight Eagles listed out, including TE Dallas Goedert (MCL sprain) and LB Zack Baun (concussion).
Eagles vs Jaguars Key Matchup Notes
- London logistics: Kickoff is 2:30 PM local time (9:30 AM ET) at Tottenham Hotspur Stadium, with Jacksonville as the designated home team.
- Eagles backfield: With Bigsby headed to IR and Barkley week-to-week, Philadelphia’s run game faces a Jacksonville defense that has allowed 53 points in four games.
- Lawrence’s efficiency: Lawrence has eight touchdown passes against two interceptions and completed 78 percent of his throws in Cincinnati.
- Philadelphia’s recent scoring: The Eagles have scored 27 points over their past two games after scoring 48 in their first two.
- Market snapshot: DraftKings opened PHI -2.5 with a 44.5 total and now shows JAX -7 and 42.5 (DraftKings via ESPN, as of 2:18 AM PT Tuesday).
Kickoff, Venue & How to Watch Philadelphia Eagles vs Jacksonville Jaguars
- Date: Sunday, October 11, 2026
- Kickoff: 9:30 AM ET (2:30 PM BST local time, 6:30 AM PT)
- Venue: Tottenham Hotspur Stadium, London, England (neutral site; Jaguars designated home team)
- TV / Streaming: NFL Network (national broadcast of the London game). NFL+ subscribers can also stream NFL Network, and ESPN lists the game in its NFL streaming hub
Where to watch: the Philadelphia Eagles vs Jacksonville Jaguars game airs on NFL Network at 9:30 AM ET. This is the second of three 2026 NFL London Games; Jacksonville stays in London to face Houston at Wembley Stadium on Oct. 18 (ESPN). Final inactives are released about 90 minutes before kickoff.
This preview is for informational purposes only. It reports odds, injury designations and broadcast details from DraftKings via ESPN, NFL.com, team sites, ESPN and AP, and it is not gambling advice. Odds, injury statuses and inactives can change before kickoff, so confirm with official sources. If you gamble, do so legally and responsibly; help is available at 1-800-GAMBLER. Information current as of Tuesday, Oct. 6, 2026, 2:18 AM PT (5:18 AM ET) for the Eagles vs Jaguars game on October 11, 2026.