The Buffalo Bills (BUF 0-0) face the Houston Texans (HOU 0-0) on Sunday, September 13, 2026 at NRG Stadium, Houston. Kickoff is scheduled for 1:00 PM ET. The game airs on CBS. Buffalo opens as a slight road favorite in a near pick’em moneyline spot at NRG Stadium.
Below is a factual Week 1 NFL matchup preview with current DraftKings odds reported via FOX around Sept. 3, 2026, including point spread, moneyline, over/under, venue, and broadcast information. Lines may move before kickoff.
Bills vs Texans odds and betting lines
| Matchup detail | Line / info |
|---|---|
| Records | Bills 0-0 · Texans 0-0 |
| Point spread | BUF -1.5 · HOU +1.5 |
| Moneyline | BUF -118 · HOU -102 |
| Over/under | 44.5 |
| Location | NRG Stadium, Houston |
| Date | Sunday, September 13, 2026 |
| Kickoff time | 1:00 PM ET |
| TV channel | CBS |
Odds are DraftKings lines reported via FOX around Sept. 3, 2026, and may move before kickoff.
How to watch Bills vs Texans
- Date: Sunday, September 13, 2026
- Time: 1:00 PM ET
- Venue: NRG Stadium, Houston
- TV: CBS
Buffalo Bills preview
The Buffalo Bills visit Houston for Week 1 as 1.5-point road favorites (-118 moneyline). Buffalo is 0-0 entering a CBS afternoon game with a 44.5 total. The tight spread and road favorite designation at NRG Stadium define Buffalos Week 1 preview.
Houston Texans preview
The Houston Texans host Buffalo at NRG Stadium as a near pick’em underdog (+1.5, -102 moneyline). Houston opens at 0-0 on the early CBS window. Home opener atmosphere and a short spread against Buffalo frame the Texans’ Week 1 matchup preview.