Houston Astros Preview & Probable Pitcher

The Houston Astros enter Friday at 78-80 and travel to face the Athletics at Sutter Health Park. Slated starter: Hayden Wesneski (5-2, 3.50).

Track the run line, moneyline, and total listed above for this odds preview. Double-check probable pitchers and any late roster moves closer to first pitch at 9:40 PM ET.

Athletics Preview & Probable Pitcher

The Athletics sit at 63-95 hosting from Sutter Health Park. Probable starter: Jacob Lopez (6-5, 5.68).

How to watch: MLB.TV / NBC Sports CA / Space City Home Network. Odds and totals can shift through the afternoon and evening — recheck your book for the latest Houston Astros vs Athletics line before the September 25, 2026 first pitch.

Where to Watch Houston Astros vs Athletics

Tune in Friday, September 25, 2026 at 9:40 PM ET from Sutter Health Park. Broadcast coverage: MLB.TV / NBC Sports CA / Space City Home Network.