East Carolina vs Memphis Odds & Preview – Oct. 22

The East Carolina Pirates average 23.5 points per game, and the Memphis Tigers allow 22.3 heading into their Thursday meeting at Simmons Bank Liberty Stadium in Memphis, TN. The current East Carolina vs Memphis odds list Memphis -10.5 with a 54.5-point total. Kickoff is 7:30 PM ET on ESPN2; records, results, stat leaders and coaches for both sides follow.

East Carolina vs Memphis Odds, Spread & Kickoff Details

Matchup detail Line / info
Matchup East Carolina at Memphis
Records East Carolina 3-3, Memphis 5-2
Spread East Carolina +10.5 (-112), Memphis -10.5 (-108)
Moneyline East Carolina +320, Memphis -410
Total 54.5 (Over -115, Under -105)
Venue Simmons Bank Liberty Stadium, Memphis, TN
Date Thursday, October 22, 2026
Kickoff 7:30 PM ET
TV ESPN2

DraftKings East Carolina vs Memphis odds reported by ESPN, as of 5:47 AM ET on Monday, Oct. 19, 2026. Numbers can change before kickoff.

East Carolina vs Memphis Odds & Line Movement

The DraftKings spread sets Memphis at -10.5, so East Carolina sits at +10.5. Moneyline prices are East Carolina +320 and Memphis -410, with the over/under at 54.5. In implied-probability terms, the East Carolina vs Memphis odds on the moneyline translate to roughly 24% for East Carolina and 80% for Memphis, including the book’s margin.

The East Carolina vs Memphis odds did not open where they are now. The spread opened at Memphis -9.5 and has moved 1 point to Memphis -10.5. On the over/under, the number opened at 53.5 and is now 54.5, up 1 points. On the moneyline, East Carolina has gone from +310 to +320 and Memphis from -395 to -410. The juice on the spread is -112 for East Carolina and -108 for Memphis; the over is priced at -115 and the under at -105.

East Carolina Preview: Form, Season Stats & Coaching Staff

East Carolina Season So Far

East Carolina comes in at 3-3, 1-1 in conference play. In ESPN’s table, East Carolina is 6th in the American standings. The road record stands at 1-2, against 2-1 at home. Last time out (Oct. 15), East Carolina lost to UAB 30-17 on the road. Across 6 games, East Carolina has been outscored 143-141 (-2 point differential).

Every East Carolina result this season, per ESPN:

  • Sept. 5: L 10-48 at Alabama
  • Sept. 12: L 24-27 vs. App State
  • Sept. 19: W 20-17 at Old Dominion
  • Sept. 26: W 42-9 vs. North Carolina Central
  • Oct. 10: W 28-12 vs. Rice
  • Oct. 15: L 17-30 at UAB

Best result by margin: 42-9 over North Carolina Central. The toughest result was a 48-10 loss at Alabama. Those scorelines give a sense of East Carolina’s range heading into the East Carolina vs Memphis odds discussion.

East Carolina Season Stats

East Carolina is putting up 23.5 points per game and moving the ball for 339.2 yards a game, with 183.7 coming through the air and 155.5 on the ground. Defensively, the unit allows 23.8 points and 326.3 yards per game, with opponents passing for 187.5 and rushing for 138.8.

For comparison, Memphis is scoring 35.4 points per game and giving up 22.3, with 199.6 passing yards allowed per game.

East Carolina Key Players

Emory Williams leads the passing game with 655 yards on a 65.4% completion rate, along with 7 touchdowns and 2 interceptions. TJ Engleman Jr. paces the ground game at 6.9 yards per carry (490 yards, 3 touchdowns). Ray Ray Joseph Jr. is the top target with 29 catches for 272 yards. On defense, DJ Johnson Jr. leads the team in tackles (42) and Jasiyah Robinson leads in sacks (2.5).

  • Passing: Emory Williams (QB), 68/104, 655 YDS, 7 TD, 2 INT
  • Rushing: TJ Engleman Jr. (RB), 71 CAR, 490 YDS, 3 TD
  • Receiving: Ray Ray Joseph Jr. (WR), 29 REC, 272 YDS, 3 TD
  • Sacks: Jasiyah Robinson (DL), 2.5
  • Tackles: DJ Johnson Jr. (LB), 42

East Carolina Coaching Staff

Blake Harrell is in his 3rd season as East Carolina’s head coach (hired for the 2024 season). The offensive coordinator is Jordan Davis. Jordan Hankins oversees the defense.

Memphis Preview: Form, Season Stats & Coaching Staff

Memphis Season So Far

Memphis comes in at 5-2, 2-1 in conference play. Memphis currently sits 4th in the American standings (ESPN). Memphis is 3-0 at home this season and 2-2 on the road. Last time out (Oct. 16), Memphis lost to Tulane 31-17 on the road. Point differential through 7 games: +92 (248 scored, 156 allowed).

Game-by-game, here is how Memphis’s season has gone (ESPN):

  • Aug. 29: W 27-21 at UNLV
  • Sept. 5: W 42-24 vs. Arkansas State
  • Sept. 12: L 20-38 at Boise State
  • Sept. 19: W 45-21 vs. UT Martin
  • Oct. 3: W 59-8 at Charlotte
  • Oct. 10: W 38-13 vs. UAB
  • Oct. 16: L 17-31 at Tulane

The most lopsided result so far was a 59-8 win at Charlotte. The toughest result was a 38-20 loss at Boise State. For anyone tracking the East Carolina vs Memphis odds, those margins show the range of outcomes this team has produced.

Memphis Season Stats

On offense, Memphis averages 35.4 points and 511.7 total yards per game, split between 274.9 passing and 236.9 rushing yards. The defense gives up 22.3 points and 372.4 yards per game (199.6 through the air, 172.9 on the ground).

Across the line of scrimmage, East Carolina’s defense allows 326.3 yards and 23.8 points per game, while its offense produces 23.5 points a game.

Memphis Key Players

Marcus Stokes has thrown for 1,841 yards (121 of 181, 66.9%) with 18 touchdowns and 6 interceptions. The top rusher is Jaylin Carter, with 780 yards on 112 carries (7.0 per carry) and 8 touchdowns. Hunter Tipton is the top target with 22 catches for 380 yards. Mike Montgomery (47 tackles) and Elijah Kinsler (4.5 sacks) are the defensive leaders.

  • Passing: Marcus Stokes (QB), 121/181, 1,841 YDS, 18 TD, 6 INT
  • Rushing: Jaylin Carter (RB), 112 CAR, 780 YDS, 8 TD
  • Receiving: Hunter Tipton (TE), 22 REC, 380 YDS, 5 TD
  • Sacks: Elijah Kinsler (DL), 4.5
  • Tackles: Mike Montgomery (LB), 47

Memphis Coaching Staff

Charles Huff is in his first season as head coach at Memphis. Kevin Decker and David Weeks run the offense as coordinators. The defensive coordinator is Lance Guidry.

Key Betting Trends: East Carolina vs Memphis Season Stats

Season-long scoring and yardage numbers can help explain where the East Carolina vs Memphis odds landed. Every figure is from ESPN game results and season team stats.

  • East Carolina games have gone over 54.5 combined points 1 time in 6 games this season.
  • East Carolina games average 47.3 combined points.
  • Memphis games have gone over 54.5 combined points 4 times in 7 games this season.
  • Memphis games average 57.7 combined points.
  • East Carolina is 1-2 in road games; Memphis is 3-0 at home.
  • Scoring offense: East Carolina 23.5 vs. Memphis 35.4 points per game.
  • Scoring defense: East Carolina allows 23.8; Memphis allows 22.3.
  • Total offense: East Carolina 339.2 vs. Memphis 511.7 yards per game.
  • This is a conference game for both teams.

East Carolina vs Memphis Series History

East Carolina and Memphis met one time in the 2024 and 2025 regular seasons, per ESPN. East Carolina won the most recent meeting. Past results are history only; the current East Carolina vs Memphis odds are in the table above.

  • Nov. 15, 2025: East Carolina 31, Memphis 27 at Dowdy-Ficklen Stadium

How to Watch East Carolina vs Memphis: TV, Time & Venue

  • Date: Thursday, October 22, 2026
  • Kickoff: 7:30 PM ET
  • TV: ESPN2
  • Venue: Simmons Bank Liberty Stadium, Memphis, TN

The game airs on ESPN2, according to ESPN. Check back for refreshed East Carolina vs Memphis odds closer to kickoff, since lines move during the week. Full matchup info is on the ESPN game page.

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Frequently Asked Questions: East Carolina vs Memphis

What are the East Carolina vs Memphis odds?

As of 5:47 AM ET on Monday, Oct. 19, 2026, the East Carolina vs Memphis odds at DraftKings are Memphis -10.5 on the spread, East Carolina +320 and Memphis -410 on the moneyline, and 54.5 on the total.

What time is East Carolina vs Memphis, and what channel is it on?

The game starts at 7:30 PM ET on Thursday, October 22, 2026 and airs on ESPN2. The East Carolina vs Memphis odds in this preview were last pulled at 5:47 AM ET.

What stadium hosts East Carolina vs Memphis?

Simmons Bank Liberty Stadium in Memphis, TN is the site; it is the home stadium of the Memphis Tigers.

Who are the head coaches for East Carolina and Memphis?

Blake Harrell coaches East Carolina, and Charles Huff coaches Memphis.