The No. 13 Missouri Tigers (5-1) visit the No. 9 Ole Miss Rebels (4-1) on Saturday, October 17, 2026 at Vaught-Hemingway Stadium, Oxford, MS. Kickoff is scheduled for 3:30 PM ET, and the game airs on SEC Network. DraftKings lists the spread at MISS -6 with a total of 59.5; moneylines are Missouri +185 · Ole Miss -225. Below is our Missouri vs Ole Miss preview with the latest odds, point spread, moneyline, over/under, kickoff time, TV channel and where to watch, plus a look at each team’s season so far, head coach and key players. Lines may move before kickoff.
Missouri vs Ole Miss Odds, Spread, Kickoff Time & TV
| Matchup detail | Line / info |
|---|---|
| Matchup | No. 13 Missouri at No. 9 Ole Miss |
| Records | Missouri 5-1 · Ole Miss 4-1 |
| Spread | MISS -6 |
| Moneyline | Missouri +185 · Ole Miss -225 |
| Total | 59.5 |
| Venue | Vaught-Hemingway Stadium, Oxford, MS |
| Date/Time | Saturday, October 17, 2026 · 3:30 PM ET |
| TV / How to Watch | SEC Network |
| Head Coaches | Missouri: HC Eli Drinkwitz, OC Chip Lindsey · Ole Miss: HC Pete Golding, OC John David Baker |
Missouri Preview: Season So Far, Coach & Key Players
Season so far: The Missouri Tigers are 5-1 overall, 2-1 in SEC play, and they are ranked No. 13 in this week’s AP Top 25. Results to date: Sep 3 — W 54-14 vs Arkansas-Pine Bluff; Sep 11 — W 38-21 at Kansas; Sep 19 — W 27-17 vs Troy; Sep 26 — L 31-24 at Mississippi State; Oct 3 — W 45-17 vs Florida; Oct 10 — W 27-6 vs Texas A&M. Most recently, Missouri beat Texas A&M 27-6 at home. Through 6 games, Missouri is averaging 35.8 points scored and 17.7 points allowed per game.
Head coach: Eli Drinkwitz (head coach since 2020). Offensive coordinator: Chip Lindsey. Defensive coordinators: Corey Batoon / Derek Nicholson.
Key players (2026 season stats):
- Passing leader: Austin Simmons (QB) — 107/165, 1,434 yards, 14 TD, 1 INT
- Rushing leader: Jamal Roberts (RB) — 147 carries, 828 yards, 8 TD
- Receiving leader: Cayden Lee (WR) — 42 receptions, 616 yards, 5 TD
- Sacks leader: Daeden Hopkins (EDGE) — 6.5 sacks
- Tackles leader: Nicholas Rodriguez (LB) — 63 total tackles
Strengths: An offense scoring 35.8 points per game; a defense holding opponents to 17.7 points per game; Jamal Roberts’s production on the ground (828 rushing yards). Questions: Handling a road trip to Vaught-Hemingway Stadium.
Ole Miss Preview: Season So Far, Coach & Key Players
Season so far: The Ole Miss Rebels are 4-1 overall, 2-1 in SEC play, and they are ranked No. 9 in this week’s AP Top 25. Results to date: Sep 6 — W 41-38 vs Louisville (neutral site); Sep 12 — W 41-9 vs Charlotte; Sep 19 — W 32-24 vs LSU; Sep 26 — L 52-28 at Florida; Oct 10 — W 52-17 at Vanderbilt. Most recently, Ole Miss beat Vanderbilt 52-17 on the road. Through 5 games, Ole Miss is averaging 38.8 points scored and 28.0 points allowed per game.
Head coach: Pete Golding (head coach since 2025). Offensive coordinator: John David Baker. Defensive coordinator: Bryan Brown.
Key players (2026 season stats):
- Passing leader: Trinidad Chambliss (QB) — 122/174, 1,435 yards, 11 TD, 4 INT
- Rushing leader: Kewan Lacy (RB) — 46 carries, 230 yards, 5 TD
- Receiving leader: Deuce Alexander (WR) — 32 receptions, 503 yards, 5 TD
- Sacks leader: Blake Purchase (DE) — 3.5 sacks
- Tackles leader: Luke Ferrelli (LB) — 34 total tackles
Strengths: An offense scoring 38.8 points per game; Trinidad Chambliss’s passing volume (1,435 yards). Questions: A defense allowing 28.0 points per game.
How to Watch Missouri vs Ole Miss
- Date: Saturday, October 17, 2026
- Kickoff: 3:30 PM ET
- Venue: Vaught-Hemingway Stadium, Oxford, MS
- TV / Streaming: SEC Network
Odds: DraftKings lines reported via ESPN as of October 12, 2026 2:12 AM PT (Arizona time). Lines may move before kickoff. Records, results and season stats via ESPN; coaching staffs per 2026 staff listings. This page is an informational matchup preview only.