The No. 4 Ohio State Buckeyes (5-1) visit the No. 5 Indiana Hoosiers (6-0) on Saturday, October 17, 2026 at Memorial Stadium, Bloomington, IN. Kickoff is scheduled for 12:00 PM ET, and the game airs on FOX. DraftKings lists the spread at OSU -3.5 with a total of 50.5; moneylines are Ohio State -180 · Indiana +150. Below is our Ohio State vs Indiana preview with the latest odds, point spread, moneyline, over/under, kickoff time, TV channel and where to watch, plus a look at each team’s season so far, head coach and key players. Lines may move before kickoff.
Ohio State vs Indiana Odds, Spread, Kickoff Time & TV
| Matchup detail | Line / info |
|---|---|
| Matchup | No. 4 Ohio State at No. 5 Indiana |
| Records | Ohio State 5-1 · Indiana 6-0 |
| Spread | OSU -3.5 |
| Moneyline | Ohio State -180 · Indiana +150 |
| Total | 50.5 |
| Venue | Memorial Stadium, Bloomington, IN |
| Date/Time | Saturday, October 17, 2026 · 12:00 PM ET |
| TV / How to Watch | FOX |
| Head Coaches | Ohio State: HC Ryan Day, OC Keenan Bailey / Arthur Smith · Indiana: HC Curt Cignetti, OC Mike Shanahan |
Ohio State Preview: Season So Far, Coach & Key Players
Season so far: The Ohio State Buckeyes are 5-1 overall, 3-0 in Big Ten play, and they are ranked No. 4 in this week’s AP Top 25. Results to date: Sep 5 — W 56-3 vs Ball State; Sep 12 — L 24-23 at Texas; Sep 19 — W 59-3 vs Kent State; Sep 26 — W 42-19 vs Illinois; Oct 3 — W 31-14 at Iowa; Oct 10 — W 45-16 vs Maryland. Most recently, Ohio State beat Maryland 45-16 at home. Through 6 games, Ohio State is averaging 42.7 points scored and 13.2 points allowed per game.
Head coach: Ryan Day (head coach since 2019). Offensive coordinators: Keenan Bailey / Arthur Smith. Defensive coordinators: Matt Patricia / Tim Walton.
Key players (2026 season stats):
- Passing leader: Julian Sayin (QB) — 116/163, 1,772 yards, 17 TD, 2 INT
- Rushing leader: Bo Jackson (RB) — 89 carries, 460 yards, 4 TD
- Receiving leader: Jeremiah Smith (WR) — 48 receptions, 916 yards, 11 TD
- Sacks leader: Kenyatta Jackson Jr. (DE) — 3 sacks
- Tackles leader: Earl Little Jr. (S) — 30 total tackles
Strengths: An offense scoring 42.7 points per game; a defense allowing only 13.2 points per game; Julian Sayin’s passing volume (1,772 yards). Questions: Handling a road trip to Memorial Stadium.
Indiana Preview: Season So Far, Coach & Key Players
Season so far: The Indiana Hoosiers are 6-0 overall, 3-0 in Big Ten play, and they are ranked No. 5 in this week’s AP Top 25. Results to date: Sep 5 — W 52-16 vs North Texas; Sep 12 — W 55-0 vs Howard; Sep 19 — W 38-0 vs Western Kentucky; Sep 25 — W 29-23 vs Northwestern; Oct 3 — W 47-15 at Rutgers; Oct 10 — W 20-17 at Nebraska. Most recently, Indiana beat Nebraska 20-17 on the road. Through 6 games, Indiana is averaging 40.2 points scored and 11.8 points allowed per game.
Head coach: Curt Cignetti (head coach since 2024). Offensive coordinator: Mike Shanahan. Defensive coordinator: Bryant Haines.
Key players (2026 season stats):
- Passing leader: Josh Hoover (QB) — 88/129, 1,364 yards, 17 TD
- Rushing leader: Turbo Richard (RB) — 71 carries, 597 yards, 5 TD
- Receiving leader: Charlie Becker (WR) — 30 receptions, 529 yards, 8 TD
- Sacks leader: Tobi Osunsanmi (DL) — 5 sacks
- Tackles leader: Isaiah Jones (LB) — 46 total tackles
Strengths: An unbeaten 6-0 start; an offense scoring 40.2 points per game; a defense allowing only 11.8 points per game. Questions: Holding serve at Memorial Stadium against Ohio State.
How to Watch Ohio State vs Indiana
- Date: Saturday, October 17, 2026
- Kickoff: 12:00 PM ET
- Venue: Memorial Stadium, Bloomington, IN
- TV / Streaming: FOX
Odds: DraftKings lines reported via ESPN as of October 12, 2026 2:12 AM PT (Arizona time). Lines may move before kickoff. Records, results and season stats via ESPN; coaching staffs per 2026 staff listings. This page is an informational matchup preview only.