Our Texans vs Titans preview covers the latest odds, point spread, moneyline, total, kickoff time, TV channel and where to watch for the NFL Week 5 matchup between the Houston Texans (0-4) and the Tennessee Titans (0-4) on Sunday, October 11, 2026, at Nissan Stadium in Nashville, TN. Kickoff is 1:00 PM ET (10:00 AM PT), and the game airs on CBS.
Week 5 storyline: Two winless AFC South teams meet in Nashville. Houston has lost four games by a combined 25 points, including a 34-30 loss to Dallas on a touchdown with 40 seconds left, while Tennessee is 0-4 in its first season under Robert Saleh and fell 24-18 at Baltimore last week (AP, ESPN).
As of Tuesday, Oct. 6, 2026, 2:18 AM PT (5:18 AM ET), DraftKings via ESPN lists the Texans as 7-point favorites over the Titans, with the moneyline at Texans -345 / Titans +275 and the over/under at 39.5. Since the open, the spread has moved from HOU -3.5 to HOU -7 and the total has moved from 43.5 to 39.5. Below are the full Texans vs Titans odds, both team previews, the latest Week 5 injury news and TV details.
Texans vs Titans Odds & Preview Info
| Matchup detail | Line / info |
|---|---|
| Matchup | Houston Texans at Tennessee Titans |
| Records | Texans 0-4 (0-1 road) · Titans 0-4 (0-2 home) |
| Spread | Texans -7 (-105) · Titans +7 (-115) |
| Moneyline | Texans -345 · Titans +275 |
| Total | 39.5 (Over -110 / Under -110) |
| Venue | Nissan Stadium, Nashville, TN |
| Date/Time | Sunday, October 11, 2026 · 1:00 PM ET (10:00 AM PT) |
| TV | CBS |
| Head Coaches | Texans: DeMeco Ryans · Titans: Robert Saleh |
| Starting QBs | Texans: C.J. Stroud · Titans: Cam Ward |
Odds: DraftKings via ESPN as of Tuesday, Oct. 6, 2026, 2:18 AM PT (5:18 AM ET). Opening line: HOU -3.5, total 43.5, moneyline Texans -192 / Titans +160. Line movement: the spread has moved from HOU -3.5 to HOU -7, the total has moved from 43.5 to 39.5, and the moneyline has gone from Texans -192 / Titans +160 at the open to Texans -345 / Titans +275. Spread and total prices are shown in parentheses. Lines can move before kickoff.
Houston Texans Preview
2026 results through Week 4: Week 1: vs Bills, L 31-36 · Week 2: vs Bengals, L 6-20 · Week 3: at Colts, L 17-19 · Week 4: vs Cowboys, L 30-34. Points: 84 scored, 109 allowed.
Season so far: Houston lost 36-31 to Buffalo on a late Josh Allen touchdown pass, 20-6 to Cincinnati, 19-17 at Indianapolis on a field goal with 16 seconds left and 34-30 to Dallas. Three of the four losses came at home (AP).
Quarterback and key players: C.J. Stroud is 93 of 151 for 1,141 yards with five touchdowns and no interceptions (ESPN), including 347 yards last week. Nico Collins returned from a hamstring injury in Week 4. David Montgomery has 127 rushing yards, Dalton Schultz leads with 21 catches for 214 yards, Will Anderson Jr. has 4.5 sacks and S Reed Blankenship has 34 tackles.
This week: DeMeco Ryans said the Texans plan to open WR Tank Dell’s 21-day practice window this week as Dell returns from ACL and MCL surgery. LB Azeez Al-Shaair (groin) is listed out, and CB Jaylin Smith (hamstring), DT Jaden Crumedy (shoulder) and LB Kenneth Murray Jr. (head) were hurt against Dallas (ESPN, Houston Chronicle).
Tennessee Titans Preview
2026 results through Week 4: Week 1: vs Jets, L 10-23 · Week 2: vs Eagles, L 20-24 · Week 3: at Giants, L 7-12 · Week 4: at Ravens, L 18-24. Points: 55 scored, 83 allowed.
Season so far: Tennessee lost 23-10 to the Jets, 24-20 to Philadelphia on a touchdown with nine seconds left, 12-7 at the Giants and 24-18 at Baltimore, where Derrick Henry scored against his former team (AP).
Quarterback and key players: Cam Ward is 75 of 119 for 726 yards with three touchdowns and two interceptions (ESPN). Rookie WR Carnell Tate leads with 22 catches for 268 yards after a 145-yard game in Baltimore, Tony Pollard has 221 rushing yards, Jeffery Simmons has two sacks and LB Anthony Hill Jr. leads the team with 42 tackles.
This week: The Titans placed guards Jackson Slater (foot) and Fernando Carmona (ankle) on injured reserve last week, so the interior line has been reshuffled. Tennessee carries no other designations on ESPN’s tracker entering the week (ESPN, team site).
Texans vs Titans Key Injuries
Source: ESPN’s injury tracker as of Tuesday, Oct. 6, 2026, 2:18 AM PT (5:18 AM ET), with team-site, ESPN and NFL Network reporting for context. These are tracker statuses after Week 4, not official game designations: official Week 5 reports for this game run Wednesday through Friday, with game designations on Friday, Oct. 9. Some players listed questionable left Week 4 games and have not been updated yet.
Houston Texans — Out: LB Azeez Al-Shaair (groin) · Doubtful: none · Questionable: DT Jaden Crumedy (shoulder); CB Jaylin Smith (hamstring); LB Kenneth Murray Jr. (head) · Recent injured reserve moves (ESPN): WR Tank Dell (knee – ACL and MCL surgery); RB British Brooks (hamstring).
Tennessee Titans — Out: none · Doubtful: none · Questionable: none · Recent injured reserve moves (ESPN): G Jackson Slater (foot); G Fernando Carmona (ankle sprain).
Context: Houston’s Tank Dell remains on injured reserve until the Texans activate him; opening his practice window starts a 21-day period.
Texans vs Titans Key Matchup Notes
- Stroud’s efficiency: Stroud has not thrown an interception in 151 attempts and threw for 347 yards against Dallas.
- Anderson vs a reshuffled interior: Anderson has 4.5 sacks, and Tennessee has two guards on injured reserve.
- Ward and Tate: Tate had nine catches for 145 yards in Baltimore and leads the Titans in receiving.
- Close games: Three of Houston’s losses were by five points or fewer, as were two of Tennessee’s.
- Market snapshot: DraftKings opened HOU -3.5 with a 43.5 total and now shows HOU -7 and 39.5 (DraftKings via ESPN, as of 2:18 AM PT Tuesday).
Kickoff, Venue & How to Watch Houston Texans vs Tennessee Titans
- Date: Sunday, October 11, 2026
- Kickoff: 1:00 PM ET (10:00 AM PT)
- Venue: Nissan Stadium, Nashville, TN
- TV / Streaming: CBS (regional broadcast; check local listings). Streaming: Paramount+ carries the local CBS feed, NFL+ streams local games on phones and tablets, and out-of-market viewers can use NFL Sunday Ticket on YouTube / YouTube TV
Where to watch: the Houston Texans vs Tennessee Titans game airs on CBS at 1:00 PM ET. Final inactives are released about 90 minutes before kickoff.
This preview is for informational purposes only. It reports odds, injury designations and broadcast details from DraftKings via ESPN, NFL.com, team sites, ESPN and AP, and it is not gambling advice. Odds, injury statuses and inactives can change before kickoff, so confirm with official sources. If you gamble, do so legally and responsibly; help is available at 1-800-GAMBLER. Information current as of Tuesday, Oct. 6, 2026, 2:18 AM PT (5:18 AM ET) for the Texans vs Titans game on October 11, 2026.