Astros vs. Mariners Preview: Odds, Spread, Time & TV (September 23, 2026)

The Houston Astros (77-79) visit the Seattle Mariners (73-83) on Wednesday, September 23, 2026 at T-Mobile Park. First pitch is set for 10:00 PM ET. TV: ESPN / Space City Home Network.

Houston Astros vs Seattle Mariners Odds & Preview Info

Matchup Houston Astros @ Seattle Mariners
Records Houston Astros 77-79 | Seattle Mariners 73-83
Run Line TBD
Moneyline Houston Astros: TBD | Seattle Mariners: TBD
Total TBD
Venue T-Mobile Park
Date / Time Wednesday, September 23, 2026 — 10:00 PM ET
TV / How to Watch ESPN / Space City Home Network
Probable Pitchers Houston Astros: TBD | Seattle Mariners: George Kirby (9-11, 4.24)

Some odds TBD / not fully posted at research time via public sportsbooks (lines move — verify before betting).

Houston Astros Preview & Probable Pitcher

The Houston Astros enter Wednesday at 77-79 and travel to face the Seattle Mariners at T-Mobile Park. Slated starter: TBD.

Track the run line, moneyline, and total listed above for this odds preview. Double-check probable pitchers and any late roster moves closer to first pitch at 10:00 PM ET.

Seattle Mariners Preview & Probable Pitcher

The Seattle Mariners sit at 73-83 hosting from T-Mobile Park. Probable starter: George Kirby (9-11, 4.24).

How to watch: ESPN / Space City Home Network. Odds and totals can shift through the afternoon and evening — recheck your book for the latest Houston Astros vs Seattle Mariners line before the September 23, 2026 first pitch.

Where to Watch Houston Astros vs Seattle Mariners

Tune in Wednesday, September 23, 2026 at 10:00 PM ET from T-Mobile Park. Broadcast coverage: ESPN / Space City Home Network.