The Seattle Seahawks (1-0) face the Arizona Cardinals (1-0) on Sunday, September 20, 2026 at State Farm Stadium, Glendale, AZ. Kickoff is scheduled for 4:25 PM ET. The game airs on FOX. This NFL Week 2 regular-season matchup is listed with the kickoff and TV details below.
Below is a factual NFL Week 2 matchup preview with current odds information, including point spread, moneyline, over/under, venue, kickoff time, and TV. This is an informational odds and broadcast preview only — no projected winner or betting advice. Lines may move before kickoff.
Seahawks vs Cardinals odds and betting lines
| Matchup detail | Line / info |
|---|---|
| Records | Seahawks 1-0 · Cardinals 1-0 |
| Point spread | SEA -4.5 ·
How to watch Seahawks vs Cardinals
Seattle Seahawks previewThe Seattle Seahawks enter this Week 2 road matchup at 1-0 after Week 1. The Seahawks travel to face the Cardinals at State Farm Stadium with kickoff set for 4:25 PM ET on FOX. Public odds boards have the Seahawks listed at -225 on the moneyline as road favorites on the posted SEA -4.5 line. The consensus total sits near 41.5. This page is an odds, spread, kickoff, and TV preview only — recheck lines and availability closer to Sunday, September 20, 2026. Arizona Cardinals previewThe Arizona Cardinals host Week 2 action at State Farm Stadium at 1-0 after Week 1. The Cardinals are listed as home underdogs on the ARI +4.5 spread with a +185 moneyline. Broadcast coverage is on FOX at 4:25 PM ET. Use the table above for the latest listed spread, moneyline, and total, and confirm where to watch in your market before kickoff. Seahawks vs Cardinals kickoff and TV infoMark your calendar for Sunday, September 20, 2026 at 4:25 PM ET. The Seattle Seahawks vs Arizona Cardinals Week 2 game is scheduled from State Farm Stadium, Glendale, AZ and airs on FOX. Odds can shift through the week — refresh your book for the current point spread, moneyline, and over/under before the ball is kicked. ARI +4.5 |
| Moneyline | SEA -225 · ARI +185 |
| Over/under | 41.5 |
| Location | State Farm Stadium, Glendale, AZ |
| Date | Sunday, September 20, 2026 |
| Kickoff time | 4:25 PM ET |
| TV channel | FOX |
Odds shown via DraftKings@ESPN / public sportsbooks. Lines may move before kickoff — verify at your sportsbook. Some shops may show slight differences versus ESPN consensus.