Louisiana faces No. 14 USC on Saturday, September 12, 2026 at Los Angeles Memorial Coliseum, Los Angeles, CA. Kickoff is scheduled for 11:00 PM ET. The game airs on BTN. Below is a factual Week 2 college football matchup preview with current odds where available, including point spread, moneyline, over/under, venue, and broadcast information. Lines may move before kickoff.
Louisiana vs USC odds and betting lines
| Matchup detail | Line / info |
|---|---|
| Records | Louisiana — · USC 2-0 |
| Point spread | USC -30.5 |
| Moneyline | TBD — check public books closer to kickoff |
| Over/under | 60.5 |
| Location | Los Angeles Memorial Coliseum, Los Angeles, CA |
| Date | Saturday, September 12, 2026 |
| Kickoff time | 11:00 PM ET |
| TV channel | BTN |
Odds: DraftKings lines reported via ESPN around research time. Lines may move before kickoff.
How to watch Louisiana vs USC
- Date: Saturday, September 12, 2026
- Time: 11:00 PM ET
- Venue: Los Angeles Memorial Coliseum, Los Angeles, CA
- TV: BTN
Louisiana preview
Louisiana (—) visits USC on Saturday, September 12, 2026. Louisiana lists head coach Michael Desormeaux, offensive coordinator Tim Leger, and defensive coordinator Jim Salgado. Early watch items include opening identity after Week 1, explosive-play balance, and matching the opponent's tempo in a BTN window.
No. 14 USC preview
No. 14 USC (2-0) hosts at Los Angeles Memorial Coliseum. USC lists head coach Lincoln Riley, offensive coordinator Luke Huard, and defensive coordinator Gary Patterson. Home-field framing, early-season continuity, and situational football are the factual focus points for this Week 2 preview.